Dietary exposure to low-calorie sweeteners in a sample of Brazilian pregnant women

The dietary exposure to low-calorie sweeteners (LCS) was estimated in a sample of pregnant Brazilian women. Consumption data were obtained with a 24-h Dietary Recall interview. Because of the uncertainty in assessing foods with LCS, they were classified into three scenarios to ensure inclusion of the 15 LCS allowed for use in Brazil: ranging from a less to a more conservative scenario. The concentration of LCS was estimated using the amount declared on the label or the maximum permitted levels and analytical determination data for table-top sweeteners. The frequency of consumption was higher for acesulfame-K, aspartame, and cyclamate. The food groups contributing the most to the consumption of LCS were non-alcoholic beverages, table-top sweeteners, confectionary and desserts. The level of dietary exposure to LCS was within the safety limit. However, continued efforts to monitor their dietary exposure are necessary given the limitations highlighted in this study.

本研究针对巴西孕妇样本，评估了其摄入低热量甜味剂（low-calorie sweeteners, LCS）的膳食暴露量。研究通过24小时膳食回顾访谈（24-h Dietary Recall interview）采集消费数据。鉴于对添加低热量甜味剂的食品进行评估存在不确定性，本研究设置三类评估场景，以覆盖巴西许可使用的全部15种低热量甜味剂，场景保守程度由低至高递增。低热量甜味剂的浓度通过标签标注含量、最大许可使用量，以及餐桌甜味剂（table-top sweeteners）的分析测定数据进行估算。安赛蜜（acesulfame-K）、阿斯巴甜（aspartame）以及甜蜜素（cyclamate）的消费频率更高。对低热量甜味剂消费贡献占比最高的食品类别为无酒精饮料、餐桌甜味剂、糖果及甜点。受试者的低热量甜味剂膳食暴露水平处于安全限值范围内。但鉴于本研究揭示的局限性，仍需持续开展监测以跟踪人群的低热量甜味剂膳食暴露情况。