Crystal structure of P.aeruginosa LpxC in complex with inhibitor
收藏Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of P.aeruginosa LpxC in complex with inhibitor Descriptor: 4-[(1~{R},5~{S})-6-[2-[4-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]phenyl]ethynyl]-3-azabicyclo[3.1.0]hexan-3-yl]butanoic acid, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION Authors: Mima, M, Ushiyama, F, Takashima, H. Deposit date: 2020-11-04 Release date: 2021-01-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg.Med.Chem., 30, 2020
创建时间：
2020-11-04
