Additional file 2 of Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evolution
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Additional file 2: Additional Table S2. List of human population samples per HLA locus. For each sample, its population name, it country and region, the population size as well as heterozygosity (H) and nucleotide diversity (π), allelic richness (ar) and the results of the Slatkin Ewens-Watterson test of neutrality and Hardy-Weinberg (HW) equilibrium are given. The table presents also the results of the simulations for diversity indices (average value and standard deviation, and the confidence interval at 95% on the 1000 sub-samples); the results of the simulations for Hardy-Weinberg test (proportion of rejections of HW test in the 1000 sub-samples); the results of the simulations for Ewens-Watterson test (proportion of rejections of Ewens-Watterson test (rejections for both an excess of homozygotes or of heterozygotes) in the 1000 sub-samples).
附加文件2:补充表S2。各人类白细胞抗原(HLA)基因座的人群样本列表。针对每份样本,本表格提供了其种群名称、所属国家与地区、种群规模,以及杂合度(H)、核苷酸多样性(π)、等位基因丰富度(ar),还有Slatkin-Ewens-Watterson中性检验与哈迪-温伯格(HW)平衡检验的结果。此外,本表格还涵盖了多样性指数的模拟结果(1000次子抽样下的均值、标准差及95%置信区间);哈迪-温伯格检验的模拟结果(1000次子抽样中HW检验被拒绝的比例);以及Ewens-Watterson检验的模拟结果(1000次子抽样中Ewens-Watterson检验被拒绝的比例——包含纯合子过剩或杂合子过剩两种情形下的拒绝结果)。
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figshare
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2020-09-16



