five

baicalein and SVCV combinatorial effects

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP599064
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This eukaryotic reference-based transcriptome study investigates the combinatorial effects of BAI drug treatment and SVCV viral infection in EPC cells.We analyzed four experimental groups:1.NC Healthy Control\uff1aUntreated, uninfected baseline group.2.Exposed to BAI compound to assess drug-specific transcriptional responses.3.Infected with SVCV virus to characterize host-pathogen interactions.4.Co-treated with BAI and SVCV to evaluate drug-mediated modulation of antiviral responses.Data generated via RNA-seq were aligned to the reference genome Pimephales promelas to identify differentially expressed genes and functional pathways.Key analyses include: Comparative DEG profiling across all treatment pairs. Enrichment analysis of immune related pathways. Validation of candidate genes regulating drug-virus interactions. This dataset provides insights into the molecular mechanisms of baicalein in augmenting antiviral immunity and potential therapeutic applications.
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2025-09-30
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