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A Highly Diastereo- and Enantioselective Synthesis of Multisubstituted Cyclopentanes with Four Chiral Carbons by the Organocatalytic Domino Michael−Henry Reaction

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/A_Highly_Diastereo_and_Enantioselective_Synthesis_of_Multisubstituted_Cyclopentanes_with_Four_Chiral_Carbons_by_the_Organocatalytic_Domino_Michael_Henry_Reaction/2919421
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资源简介:
Highly functionalized cyclopentanes with four stereogenic carbons including two quaternary stereocenters have been synthesized in excellent yields (90−95%) with complete diastereoselectivities and excellent enantioselectivities (88−96% ee) by the organocatalyzed asymmetric domino Michael−Henry reaction.
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2016-02-27
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