Germinal Center Lymphoma versus Hyperplasia
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http://flowrepository.org/id/FR-FCM-ZZ6B
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资源简介：
Data sets to address the question ?What is the best flow cytometric analysis strategy to distinguish germinal center B-cell lymphoma from reactive lymphoid tissue using the 8-color antibody combination: anti-kappa, anti-lambda, CD19, CD20, CD10, CD5, CD38 and CD45 antibodies?? Germinal center lymphoma, n=48. Lymphoid hyperplasia, including germinal center cells, n=52.
Conclusion:
Application of the computational tools flowType and RchyOptimyx (cellular hieraRCHY OPYIMization) highlighted the diagnostic utility of identifying CD10 positive, CD38 negative B-cells in the distinction between GC-L and GC-H. Clinical laboratory procedures employed to reduce sources of variability including standardized sample preparation and staining, lot-to-lot comparison of reagents, and cloning of instrument settings.
创建时间：
2013-05-01
