m6A-eCLIP analysis of human macrophages
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE210619
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资源简介：
N6-methyladenosine (m6A) is the most abundant mRNA modification in mammalian cells, mediated co-transcriptionally by a methyltransferase ‘writer’ complex containing METTL3 as the S-adenosyl methionine (SAM)-binding subunit as well as adaptors such WTAP and ZC3H13 To profile m6A mRNA modification sites transcriptome-wide with single nucleotide resolution, we performed enhanced crosslinking and immunoprecipitation (m6A-eCLIP) in WTAP-, ZC3H13-, METTL3-deficient and NTC control cells derived from two healthy donors. Additionally we profiles BMDMs from 2 independent mice. All samples were treated with LPS for 3h. **Raw data will be submitted to EGA**
创建时间：
2024-11-13
