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Genome-wide mapping of miRNAs expressed in embryonic stem cells and pluripotent stem cells generated by different reprogramming strategies

ChEBI2014-07-05 更新2026-07-21 收录

干细胞miRNA表达谱

多能性重编程机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-52950 数据链接链接失效反馈

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资源简介：

Genome-wide mapping of miRNAs expressed in embryonic stem cells and pluripotent stem cells generated by different reprogramming strategies

应用场景：

创建时间：

2014-07-05

范可尼贫血分子机制

干细胞miRNA表达谱

Fanconi anemia (FA) is a rare genetic disorder characterized by genomic instability, developmental defects and bone marrow failure. Homeostasis of hematopoietic stem cells (HSCs) in the bone marrow pa

NIAID Data Ecosystem80

miR expression profiling of mouse hematopoietic stem and progenitor populations [miRNA]. Mus musculus

干细胞miRNA表达谱

miRNA-mRNA互作网络预测

Several individual miRNAs (miRs) have been implicated as potent regulators of important processes during normal and malignant hematopoiesis. In addition, many miRs have been shown to fine-tune intrica

NIAID Data Ecosystem40

Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2 [CHIP-Seq]

多能性重编程机制

转录因子互作

Oct4, along with Sox2 and Klf4 (SK), can induce pluripotency but structurally similar factors like Oct6 cannot. To decode why Oct4 has this unique ability, we compare Oct4-binding, accessibility patte

NIAID Data Ecosystem30

miRNA expression in BMSCs. miRNA expression in BMSCs

成骨软骨分化调控

干细胞miRNA表达谱

We performed microarray analysis to determine the expression profiles of miRNAs during osteoblast differentiation of BMSCs Overall design: BMSCs were cultured in osteogenic medium for 7 days. We perfo

NIAID Data Ecosystem70

Differential expressed miRNAs up-regulated in both two types of piPSCs compared with pEFs (|log 2 (FC)|≥1, total counts >10, P-value < 0.05).

干细胞miRNA表达谱

差异表达分析

Differential expressed miRNAs up-regulated in both two types of piPSCs compared with pEFs (|log2(FC)|≥1, total counts >10, P-value < 0.05).

NIAID Data Ecosystem30