Disease distrupts shrimp gut community assembly

Shrimp offers an ideal model for studying interactions between hosts and their associated microbiota. In addition, the frequent occurrences of shrimp disease enable us to evaluate the response of gut microbiota to disease. It is long recognized that the function of gut physiology increases as host matured. Thus, we hypothesized that the ability of host selection on external taxa increases with maturity, while this trend would be skewed when disease occurred. To achieve this, we adopt the natural model in which consider the gut bacterial community of shrimp to be local communities that are a part of a broader metacommunity, that is, the rearing bacterioplankton communities. Given that gut microbiota contributes fundamental roles in pathogen resistance, we speculated the antagonistic interactions between opportunistic pathogens and resident taxa will shift to synergic interactions. we discerned interspecies interaction of candidate pathogens over developmental stages and between health status.