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SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE99596
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Protein deacetylase SIRT7 is significantly downregulated in lung metastases of human patient and mouse tissues, and predicted metastasis-free survival. To explore the roles of SIRT7 in breast cancer, we analysed the gene expressions in breast cancer BT549 cells with SIRT7 knockdown or not. The mRNA profiles of breast cancer BT549 cells with SIRT7 knockdown or not were generated by deep sequencing using Illumina HiSeq-2000
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2021-09-29
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