Time-course alterations of gut microbiota after short-term lincomycin exposure in young swine

Increasing evidence suggests that antibiotic administration causes gut injury, nutrient digestion, immune regulation and colonization resistance against pathogens due to the disruption of gut microbiota. However, the time-course effects of therapeutic antibiotics on alterations of gut microbes and short-chain fatty acid in young swine are still unknown. In this study, twenty piglets were assigned into two groups and fed commercial diets with or without lincomycin in first week for 28-day trial period.