Dataset_08_11_18.dta

We conducted a prospective monocentric study on a convenience sample of patients admitted to the ED from December 2017 to April 2018. Patients aged 18-99 presenting to the ED for whom the treating clinician deemed necessary an arterial blood gas analysis (BGA) were screened for inclusion in the study if not pregnant. Screening for inclusion was performed according to study personnel availability and overall workload in the ED. We calculated a sample size of 200 patients based on previous study²¹ reporting a standard deviation of differences for pH of 0.0338. We based our sample calculation on the precision of the estimates and aimed for a standard error of the 95% limit of agreement of approximatively +/- 0.01. Simultaneous arterial and capillary samples were drawn for BGA. Arterial BGA were sampled by direct arterial radial or femoral puncture using a pre-heparinized syringe (safe-PICO aspirator®, 1,7ml, Radiometer® and a 23G needle (BD Microlance® 3, Becton Dickinson®). Capillary samples were obtained at patients finger using a contact-activated lancet (BD Microtainer®, Becton dickinson®) and collected through capillary tubes (safeCLINITUBES® 70µl, Radiometer®). Samples were analyzed with the same Point of care BGA analyzer (ABL90 FLEX® Radiometer®). Analysis of samples was not blinded, clinical information, index test results and reference standard results were available to the assessors of the reference standard.