MEK1 bound to DS03090629
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MEK1 bound to DS03090629 Descriptor: (1~{R},3~{S})-3-[[6-[2-chloranyl-4-(4-methylpyrimidin-2-yl)oxy-phenyl]-3-methyl-1~{H}-indazol-4-yl]oxy]cyclohexan-1-amine, CALCIUM ION, DIMETHYL SULFOXIDE, ... Authors: Kishikawa, S, Takano, K, Ubukata, O, Hanzawa, H. Deposit date: 2022-04-22 Release date: 2023-03-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma. Mol.Cancer Ther., 22, 2023
创建时间：
2022-04-22
