Co-crystal structure of BTK kinase domain with Zanubrutinib
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Co-crystal structure of BTK kinase domain with Zanubrutinib Descriptor: (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, IMIDAZOLE, Tyrosine-protein kinase BTK Authors: Zhou, X, Hong, Y. Deposit date: 2019-01-15 Release date: 2019-10-23 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase. J.Med.Chem., 62, 2019
创建时间：
2019-01-15
