FA-8B

FA-8B investigates the impact of <i>Bifidobacterium</i> <i>bifidum</i> treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample FA-8B:<br>F: Denotes the strain ST-42 of Clostridioides difficile.<br>A: Represents timepoint 1, indicating sampling before C. difficile infection.<br>8: Refers to the specific mouse number under investigation.<br>B: Indicates the treatment administered, which in this case is <i>Bifidobacterium</i> <i>bifidum</i>.

本数据集（FA-8B）旨在探究双歧杆菌（Bifidobacterium bifidum）干预对艰难梭菌（Clostridioides difficile）感染小鼠的肠道菌群影响。研究人员采集感染后小鼠的粪便样本，采用Invitrogen相关方案进行前处理，并于Ion Torrent下一代测序（NGS）系统上完成测序。通过Ion Reporter SW（16S）开展分析后发现，在感染后第1、3、6天，微生物类群的动态丰度发生显著变化，该研究可为艰难梭菌感染期间益生菌调节肠道菌群的潜在作用提供理论参考。

样本FA-8B的命名规则如下：
- 字母F：代表艰难梭菌菌株ST-42；
- 字母A：代表采样时间点1，即艰难梭菌感染前的采样节点；
- 数字8：指代本次研究中的特定小鼠编号；
- 字母B：代表所施加的干预手段，即本次使用的双歧杆菌（Bifidobacterium bifidum）干预。