Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA482850
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资源简介：
To characterize the in vivo role of DROSHA mutations during kidney development and their oncogenic potential, we analyzed mouse lines with either a targeted deletion of Drosha or an inducible expression of human DROSHA carrying a tumor-specific E1147K mutation that acts in a dominant negative manner. Overall design: Examination of miRNA expression of whole E16.5 kidneys in two different mouse lines
创建时间：
2018-07-25
