Implication of Nos2 inactivation on genomic changes in Ptch1+/- medulloblastomas (array-CGH)

ChEBI2011-12-01 更新2026-07-21 收录

母细胞瘤基因组学

肿瘤发生机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-29199 数据链接链接失效反馈

官方服务：

资源简介：

Implication of Nos2 inactivation on genomic changes in Ptch1+/- medulloblastomas (array-CGH)

创建时间：

2011-12-01

Gene expression profiling in mouse fibroblast tumors with overexpression of the homeoprotein SIX1

肿瘤发生机制

细胞衰老调控

Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results also show that SIX1 acts as a repressor of cell senescence, an antiproliferative response wit

NIAID Data Ecosystem110

Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy. Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy

母细胞瘤基因组学

溶酶体靶向

Transcriptome analysis of mRNA samples from Rb/p53-deficient mouse pineoblastomas Overall design: We anlayzed 12 Rb/p53-deleted mouse pineoblastoma, 5 Rb/p53-mutated pineoblastoam, 3 Dicer1/p53-delete

NIAID Data Ecosystem50

OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks. OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks

癌症信号网络

肿瘤发生机制

We introduce a new algorithm, OncoSig, to address the deficiencies of canonical pathways through the accurate, context-specific prediction of proteins representing both known and novel functional memb

NIAID Data Ecosystem30

p53 amyloid formation induced cellular transformation and tumor formation in xenograft model

p53

肿瘤发生机制

p53 mutation and its subsequent loss of function along with gain of oncogenic functions is associated with cancer. However, the exact mechanism of how altered p53 acts as an oncogene is not clear yet.

NIAID Data Ecosystem50

Transcriptome changes following loss of Apc in the intestine. Mus musculus

肿瘤发生机制

Wnt信号通路靶基因

Nearly all colorectal cancers have dysregulated Wnt signalling, predominantly through the mutation of the Apc (Adenomatous Polyposis Coli) gene. Therefore it is of vital importance to elucidate the ke

NIAID Data Ecosystem40

Implication of Nos2 inactivation on genomic changes in Ptch1+/- medulloblastomas (array-CGH)

资源简介：

相关数据集