Data from: Epigenetically distinct synaptic architecture in clonal compartments in the teleostean dorsal pallium

The dorsal telencephalon (i.e. the pallium) exhibits high anatomical
diversity across vertebrate classes. The non-mammalian dorsal pallium
accommodates various compartmentalized structures among species. The
developmental, functional and evolutional diversity of the dorsal pallium
remain unillustrated. Here, we analyzed the structure and epigenetic
landscapes of cell lineages in the telencephalon of medaka fish (Oryzias
latipes) which possesses a clearly delineated dorsal pallium (Dd2). We
found that pallial anatomical regions, including Dd2, are formed by
mutually exclusive clonal units, and that each pallium compartment
exhibits a distinct epigenetic landscape. In particular, Dd2 possesses a
unique open chromatin pattern that preferentially targets synapse-related
genes. Indeed, Dd2 shows a high density of synapses. Finally, we
identified several transcription factors as candidate regulators. Taken
together, we suggest cell lineages are the basic components for the
functional regionalization in the pallial anatomical compartments, and
that their changes has been the driving force for evolutionary diversity.