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G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects. G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects

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Evaluation of the effect of 3 ASOs targeting FXN on mRNA levels Overall design: PolyA RNA seq for ASOs targeting the Frataxin gene. Single-end 75 cycles, 3 replicates per treatment.

创建时间:
2022-06-06
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