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Crystal structure of PDE10A2 with fragment ZT217

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of PDE10A2 with fragment ZT217 Descriptor: 2-methylquinazolin-4(3H)-one, NICKEL (II) ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Authors: Sridhar, V, Badger, J, Logan, C, Chie-Leon, B, Nienaber, V. Deposit date: 2013-07-09 Release date: 2014-02-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography. J Biomol Screen, 19, 2014

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2013-07-09
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