Additional file 9: of Genotyping, generation and proteomic profiling of the first human autosomal dominant osteopetrosis type II-specific induced pluripotent stem cells

Table S1. Proteomic analysis revealed the similar expression of pluripotency markers in the ADO2-iPSCs and NC-iPSCs. Table S2 GO functional enrichment analysis of the DEPs of the ADO2-iPSCs. Table S3 KEGG functional enrichment analysis of the DEPs of the ADO2-iPSCs. Table S4 Protein domain functional enrichment analysis of the DEPs of the ADO2-iPSCs. Table S5 GO functional enrichment analysis of the differently Khib-modified proteins of the ADO2-iPSCs. Table S6 KEGG functional enrichment analysis of the differently Khib-modified proteins of the ADO2-iPSCs. Table S7 Protein domain functional enrichment analysis of the differently Khib-modified proteins of the ADO2-iPSCs. (XLSX 32 kb)

补充表S1。蛋白质组学分析结果显示，ADO2诱导多能干细胞（ADO2-iPSCs）与阴性对照诱导多能干细胞（NC-iPSCs）的多能性标志物表达水平相似。
补充表S2。针对ADO2-iPSCs的差异表达蛋白（differentially expressed proteins, DEPs）开展基因本体（Gene Ontology, GO）功能富集分析。
补充表S3。针对ADO2-iPSCs的差异表达蛋白开展京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）功能富集分析。
补充表S4。针对ADO2-iPSCs的差异表达蛋白开展蛋白质结构域功能富集分析。
补充表S5。针对ADO2-iPSCs的差异赖氨酸2-羟基异丁酰化（lysine 2-hydroxyisobutyrylation, Khib）修饰蛋白开展基因本体功能富集分析。
补充表S6。针对ADO2-iPSCs的差异赖氨酸2-羟基异丁酰化修饰蛋白开展京都基因与基因组百科全书功能富集分析。
补充表S7。针对ADO2-iPSCs的差异赖氨酸2-羟基异丁酰化修饰蛋白开展蛋白质结构域功能富集分析。（文件格式：XLSX，大小：32 KB）