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Additional file 11: of A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes

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Table S9. Correlation between methylation and expression changes in each cancer type. K1 is number of CDGs mutated in ≥ 5 samples with expression data available; K2 is number of CDGs mutated in ≥ 5 samples with methylation data available; E is set of CDGs with pi,k’<0.05, that is, CDGs whose mutation status are significantly associated with f differentially expressed genes; M is set of CDGs with pi,k<0.05, that is, CDGs whose mutation status are significantly associated with differential methylation; ‘cor’ stands for correlation between the number of differentially methylated sites and the number of differentially expressed genes by the CDG mutation. (XLSX 9 kb)

表S9 各癌症类型中甲基化与表达变化的相关性。K1为在≥5份携带表达数据的样本中发生突变的癌症驱动基因(Cancer Driver Genes,CDGs)的数量;K2为在≥5份携带甲基化数据的样本中发生突变的CDGs的数量;E集合为满足pi,k’<0.05的CDGs,即突变状态与差异表达基因显著相关的CDGs;M集合为满足pi,k<0.05的CDGs,即突变状态与差异甲基化显著相关的CDGs;"cor"代表CDG突变对应的差异甲基化位点数量与差异表达基因数量之间的相关性。(XLSX 9 kb)
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2018-11-07
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