Synergistic Acid-Promoted Synthesis of Highly Substituted Butenolides via the Annulation of Keto Acids and Tertiary Alcohols
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https://figshare.com/articles/dataset/Synergistic_Acid_Promoted_Synthesis_of_Highly_Substituted_Butenolides_via_the_Annulation_of_Keto_Acids_and_Tertiary_Alcohols/2107048
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资源简介:
An efficient and practical approach
to highly substituted butenolides via the annulation of keto acids
and tertiary alcohols is described. The synergistic effect provided
by the combination of Lewis and Brønsted acids is crucial to
the reaction outcome. A variety of highly substituted butenolides
are readily produced in synthetically useful yields. Water is the
only waste from the reaction, therefore making it an environmentally
benign and atom-economical process for butenolide synthesis.
创建时间:
2016-02-12



