Intracerebral (IC) site-specific studies of antisauvagine-30 effects on stress- or anxiety-related endpoints.
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Note: Not only doses, but also concentrations, are listed because relative dilution of the injected concentration across a given volume of brain is what will determine the local concentration relevant to receptor pharmacodynamics. Mek-1/2 = Mitogen-activated extracellular signal-regulated kinases; CeA = central nucleus of the amygdala; BLA = basolateral amygdala; mPFC = medial prefrontal cortex; NAc = nucleus accumbens; CRF = corticotropin-releasing factor; Ucn 2 = urocortin 2.
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2015-12-02



