The influence of upper interface single-, double- and triple-mutations on activation gating of the tandem-dimer Shaker Kv channela

Figs. 4 and 5.a The table displays the gating parameters of all single-, double- and triple-mutants used to calculate the coupling free energies presented in b Mutants were generated using the tandem-dimer gene construct. Any mutation is thus present in only two diagonal channel subunits.