five

EGFR T790M/C797S in complex with compound 6i

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Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6jrx
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EGFR T790M/C797S in complex with compound 6i Descriptor: Epidermal growth factor receptor, N-{trans-4-[3-(2-chlorophenyl)-7-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]cyclohexyl}propanamide Authors: Zhu, S.J, Yun, C.H. Deposit date: 2019-04-06 Release date: 2020-04-15 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.201 Å) Cite: Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-alpha Motif Kinase (ZAK) Inhibitors. J.Med.Chem., 63, 2020
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2019-04-06
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