Comparison of mtDNA in normal, tumor, BPH, and WBCs between race after adjustment with age, Gleason, and PSA.

Adjusted mtDNA analyses were performed using two-way ANOVA, with the appropriate p-values obtained using standard bootstrap methodologies to account for the non-normal mtDNA values. For each patient group, the adjusted mean mtDNA values are presented by race (standard error presented in parentheses). “Race p-value” corresponds to the adjusted comparison of race; “factor p-value” corresponds to the effect of age, Gleason sum, or PSA on mtDNA; “interaction p-value” corresponds to testing for an interaction effect (i.e., whether the difference between race depend on the age, Gleason sum or PSA level). *There is no average for the CA in the PSA adjusted model because there is no CA with PSA >10 in the BPH.