Supporting data for "Rational design and development of an interferon-integrated universal sarbecovirus vaccine"

This is a complete dataset for the thesis "Rational design and development of an interferon-integrated universal sarbecovirus vaccine"In this study we designed a SARS-CoV-2 vaccine platform, which is interferon-beta integrated vaccine (IBIS). The designed different versions for different purposes. The vaccines were able to elicit robust antibody responses and completely protect hamsters from SARS-CoV-2 infection without causing lung pathology. The vaccine seeds and producing cell-line are generated and ready for future human trial.In the dataset folders, there are three subfolders. Inside each subfolder, there is a folder for each experiment. Inside the experiment folder, there are protocol and corresponding data. README.txt file was provided for the description of the datasets.