Dataset for 'DEM modelling of controlled drug release of push-pull osmotic pump tablets'

This dataset contains both numerical simulation data and experimental data describing the drug release performance of push-pull osmotic pump tablets. Detailed study on the swelling behaviour is presented in a journal paper entitled "DEM modelling of controlled drug release of push-pull osmotic pump tablets ". We provide all the essential data in a single excel file with the description below: Fig. 4 Comparison of drug release profiles obtained from experiment and DEM simulation. Fig. 6 Typical drug release profiles for PPOP tablets obtained numerically. Fig. 7 Drug release profiles for PPOP tablets with different orifice sizes. Fig. 8 The average release rate for (a) the burst release phase and (b) the slow-release phase with different orifice sizes. Fig. 11 Evolutions of (a) mass of drug release and (b) accumulative drug release percentage for PPOP tablets with different the ratios of drug particle number to polymer particle number. Fig. 12 The average release rate for (a) the burst release phase and (b) the slow release phase with different the ratios of drug particle number to polymer particle number. Fig. 14 Drug release profiles for PPOP tablets with different surface curvatures. Fig. 15. The average release rates for (a) the burst release phase and (b) the slow-release phase with different surface curvatures. Fig. 16. Drug release profiles for PPOP tablets with different coefficients of friction. Fig. 18. The average release rate for the burst release and slow-release phases with different coefficients of friction. Fig. 19 Drug release profiles for PPOP tablets with different surface energies between polymer particles. Fig. 21 The average release rate for (a) the burst release and (b) the slow-release phases with different surface energies between polymer particles.