Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 10 (methyl [(3R)-1-methyl-5-oxopyrrolidin-3-yl]acetate)
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 10 (methyl [(3R)-1-methyl-5-oxopyrrolidin-3-yl]acetate) Descriptor: Bromodomain-containing protein 4, methyl [(3R)-1-methyl-5-oxopyrrolidin-3-yl]acetate Authors: Ilyichova, O.V, Scanlon, M.J. Deposit date: 2019-07-11 Release date: 2019-11-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition. Bioorg.Med.Chem., 27, 2019
创建时间：
2019-07-11
