Estimated parameters for the signaling models.

Parameters shown were those that were varied during fitting between the models. Dash (-) means a parameter was fixed during fitting and they have the same values between the models, that is hi (i = 1 − 2) = 10.0, Ai (i = 1 − 3) αi(i = 1 − 4) = 0.0033, βi(i = 1 − 4) = 0.015, γi(i = 1 − 2) = 0.015. The system of equations/models (S1), (S2) and (S3) in S1 Text were used to generate the fits (Fig 2) and in estimating the parameters. Priors for α’s and β’s were set between 0–1, while for hi’s between 0–10.