Associations with risk variants at 8q24 in African Americans.

aRisk regions as defined in [1], [2], [7], [10], [13].bRisk /reference alleles.cRAF, risk allele frequency in populations of European ancestry [1], [6 or HapMap CEU] and in African Americans (AA).dAdjusted for age, study, the 1st 10 eigenvalues and local ancestry for region 127.8–129.0 Mb (NCBI build 36).eTest of trend (1-d.f.).fFrom the multivariate model. OR adjusted for age, study, the 1st 10 eigenvalues, local ancestry and all other 8q24 risk variants.gThe proportion of the variance explained by the other SNPs.hImputed (Rsq≥0.76). rs445114 was not genotyped and could not be imputed [6].iSNPs kept in stepwise procedure if p