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Crystal Structure of SARS CoV-2 Mpro mutant N142P with Pfizer Intravenous Inhibitor PF-00835231

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Protein Data Bank Japan2026-03-04 更新2026-04-11 收录
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Crystal Structure of SARS CoV-2 Mpro mutant N142P with Pfizer Intravenous Inhibitor PF-00835231 Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide Authors: Shaqra, A.M, Schiffer, C.A. Deposit date: 2022-08-19 Release date: 2024-02-07 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Contributions of Hyperactive Mutations in M pro from SARS-CoV-2 to Drug Resistance. Acs Infect Dis., 10, 2024
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2022-08-19
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