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Structural characterization of cerasomes

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ESRF Portal2025-01-01 更新2026-04-23 收录
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https://doi.esrf.fr/10.15151/ESRF-ES-685576317
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The idea is to characterize cerasomes particles. Such objects are 200 nm micelles with a mono- or bilayer of silanol lipids (<5 nm) suspended in water. Their surface is partly rigid thanks to silanol crosslinking, still those are "soft glass bubbles" and can be used for a variety of application in chemistry or biology, mainly for drug delivery. We would be interested by checking the bi- or mono- layer thickness of those micelles, indeed batch and microfluidic reactors were used for the synthesis of cerasomes and they seem to have different rigidity and therefore different layer thickness. Only SAXS would allow to characterize such dimension.
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2025-01-01
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