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资源简介：
A novel adenine base editor with high activity.
应用场景：
创建时间：
2021-03-11
相关数据集
Optimizing sgRNA structure to improve CRISPR-Cas9 knockout efficiency
The current commonly used single-guide RNA (sgRNA) structure has a shortened duplex compared with the native bacterial clustered regularly interspaced short palindromic repeats RNA (crRNA)–transactiva
NIAID Data Ecosystem60
Expression and Functional Characterization of the Agrobacterium VirB2 Amino Acid Substitution Variants in T-pilus Biogenesis, Virulence, and Transient Transformation Efficiency
Agrobacterium tumefaciens is a phytopathogenic bacterium that causes crown gall disease by transferring transferred DNA (T-DNA) into the plant genome. The translocation process is mediated by the type
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Additional file 2 of Increased prime edit rates in KCNQ2 and SCN1A via single nicking all-in-one plasmids
Additional file 2: Table S1. Individual data values of all data represented in this manuscript.
NIAID Data Ecosystem20
Natural transformation of C. jejuni at varying temperature and atmospheric conditions a,b .
aExponentially growing cells were supplied with isogenic chromosomal DNA at 1∶2.5 ratio (CFU:DNA) and transformation was allowed to proceed for 4 h before plating on selective agar. Results are the av
NIAID Data Ecosystem30
Homo sapiens and zebrafish Targeted Locus (Loci)
We find that pre-crRNAs comprising a full-length direct repeat (full-DR-crRNA) sequence with specific stem-loop G-C base substitutions exhibit increased editing efficiencies compared with the standard
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