Synthesis of a 80-member library of novel pyrano[4,3-b]quinolines in solution-phase is reported. The key intermediate, 4-iodopyrano[4,3-b]quinolines were synthesized by the electrophilic iodocyclizati

NIAID Data Ecosystem40

Antimalarial activity of BAQ and MAQ in mice infected with P. berghei after treatment with daily doses of the compounds during three consecutive days.

抗疟药物筛选

体内药效评估

*Reductions ≤30% were considered as inactive, 30–50% as partially active and ≥50% as active drugs.

Figshare2015-12-02 更新70

Bioactive Compounds from the Roots of Strophioblachia fimbricalyx

天然产物化学

抗疟药物筛选

Eight new compounds, fimbricalyxs B–D (1–3), fimbricalyxanhydrides A and B (4, 5), and fimbricalyxlactones A–C (6–8), together with three known compounds, trigonostemone (9), 3,6,9-trimethoxyphenanthr

NIAID Data Ecosystem50

P. vivax HS. Plasmodium vivax strain:30111110026

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