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ChIP-seq assays for H3K27ac. Mus musculus

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NIAID Data Ecosystem2026-03-08 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA224548
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资源简介:
By using FACS-sorted MC1-ZE7 ES cells, we analyzed the genome-wide distribution of H3K27ac and DNA methylation in Zscan4 positive ES cells (Em+) and Zscan4 negative ES cells (Em-). H3K27 hyperacetylation and DNA demethylation were detected in heterochromatic regions of Em+ cells, but not Em- cells. These results suggested that the Zscan4 state takes "open" chromatin conformation in ES cells. Overall design: H3K27ac in Zscan4 positive and negative cells
创建时间:
2013-10-24
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