Data underlying the research of Prominent Obesity-induced Systemic Inflammation Exacerbates Lupus Activity and Organ Damages in Fc Gamma Receptor IIb Deficient Lupus Mice, Impacts of Saturated Fatty Acid and Gut Barrier Defect

The impacts of obesity on lupus were explored using 8-wk-old mice with deficiency of Fc gamma receptor IIb (FcgRIIb), the only inhibitory FcγR, and with experiments on the macrophage.<br>

本研究以8周龄的Fcγ受体IIb（Fc gamma receptor IIb，FcgRIIb）缺陷小鼠为实验对象，该受体为唯一的抑制性FcγR，并通过巨噬细胞（macrophage）相关实验，探究了肥胖对狼疮的影响。