Crystal structure of human beta-secretase in complex with NVP-AFJ144
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Crystal structure of human beta-secretase in complex with NVP-AFJ144 Descriptor: (2R,4S,5S)-N-butyl-4-hydroxy-2,7-dimethyl-5-{[N-(4-methylpentanoyl)-L-methionyl]amino}octanamide, Beta-secretase 1 Authors: Rondeau, J.-M. Deposit date: 2008-07-18 Release date: 2009-02-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
创建时间:
2008-07-18



