Gene expression in E18.5 Tex19.1-/- mouse placenta

Microarray experiment to identify changes in gene expression in 18.5 day post coitum Tex19.1-/- mouse placenta. Tex19.1 is expressed in trophectoderm-derived cells in the placenta. Tex19.1-/- placentas are small and have defects in junctional zone and labyrinth layers of the placenta, Tex19.1-/- embryos exhibit intra-uterine growth retardation. Data provides insight into the changes in gene expression and cell composition in Tex19.1-/- placentas. Six E18.5 Tex19.1-/- placentas (KO: four XX, two XY), four E18.5 Tex19.1+/- littermate control placentas (HET: four XX), and two E18.5 Tex19.1+/+ littermate control placentas (WT: two XY) are included in the analysis.本研究通过基因芯片实验（Microarray experiment），旨在鉴定交配后18.5天的Tex19.1-/-小鼠胎盘中的基因表达变化。Tex19.1基因在胎盘的滋养外胚层（trophectoderm）来源细胞中表达。Tex19.1-/-小鼠胎盘体积偏小，且存在胎盘接合带与迷路层发育缺陷；同时，Tex19.1-/-胚胎会出现宫内生长迟缓（intra-uterine growth retardation）。本数据集有助于解析Tex19.1-/-胎盘中的基因表达与细胞组成变化。本次分析共纳入6个E18.5期Tex19.1-/-胎盘（KO组：4个XX型、2个XY型）、4个E18.5期Tex19.1+/-同窝对照胎盘（HET组：4个XX型）以及2个E18.5期Tex19.1+/+同窝对照胎盘（WT组：2个XY型）。