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Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-053

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6rcw
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Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-053 Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-[5-[(4~{a}~{R},8~{a}~{S})-3-cycloheptyl-4-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(furan-2-ylmethyl)prop-2-ynamide, ... Authors: Singh, A.K, Brown, D.G. Deposit date: 2019-04-11 Release date: 2019-07-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2). Bioorg.Med.Chem., 27, 2019
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2019-04-11
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