Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

Name: Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3
Creator: University of Science and Technology of China; Southern Medical University
Published: 2026-04-09T12:26:21+08:00

Mendeley Data2026-04-09 收录

癌症分子机制

HKDC1

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Source data of western blot in the study.

提供机构：

University of Science and Technology of China; Southern Medical University

Comparison of mRNA profiles of AGO2 sufficent and deficient pancreatic tissue in the LSL KRASG12D mouse model of pancreatic cancer

癌症分子机制

RNA表达谱分析

Purpose: The goals of this study are to compare NGS-derived transcripts to compare the expression of transcripts between AGO2 sufficent PDAC tissue and AGO2 deficient senescent PanINs in the mouse mo

NIAID Data Ecosystem20

PHGDH acts as an RNA-binding protein to stabilize PRKCD mRNA and promote hepatocellular carcinoma progression

癌症分子机制

RNA-蛋白质相互作用

Overexpression of PHGDH in MHCC-97H cells, enrichment of PHGDH-bound RNA by antibody, and identification of target genes using high-throughput sequencing One group of MHCC-97H cells overexpressed PHGD

NIAID Data Ecosystem10

Additional file 6 of Involvement of immune system and Epithelial–Mesenchymal-Transition in increased invasiveness of clustered circulatory tumor cells in breast cancer

癌症分子机制

生存分析模型

Additional file 6. The EMT subnetwork cox-PH results. The cox-PH analysis was implemented for the EMT subnetwork genes. The selected genes, coefficients, and p-values were reported.

Figshare2021-11-21 更新00

RNA-sequencing of HGC27 cells with and without FN1 3' UTR overexpression

癌症分子机制

ceRNA网络

As a key protein in the tumor microenvironment, FN1 has been proven to promote cancer in a variety of cancer species. However, in our previous study on gastric cancer, it was found that FN1 protein ex

NIAID Data Ecosystem10

Table_2_Bioinformatics-Driven Identification of p62 as A Crucial Oncogene in Liver Cancer.xlsx

癌症生物标志物

癌症分子机制

Liver hepatocellular carcinoma (LIHC) is the major form of liver cancer that is the fourth most common cause of cancer death worldwide. It has been reported that the multifunctional protein p62 (also

NIAID Data Ecosystem10

Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

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