RORC2 LBD complexed with compound 34
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RORC2 LBD complexed with compound 34 Descriptor: 3-cyano-N-{3-[1-(cyclopentanecarbonyl)piperidin-4-yl]-1,4-dimethyl-1H-indol-5-yl}benzamide, Nuclear receptor ROR-gamma Authors: Kauppi, B, Vajdos, F. Deposit date: 2018-03-07 Release date: 2018-09-05 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist. J. Med. Chem., 61, 2018
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2018-03-07
