Expression data from liver of Balb/c(WT) and Balb/cBy mice(KD). Expression data from liver of Balb/c(WT) and Balb/cBy mice(KD)

Free fatty acid beta oxidation and Akt signal pathway process were up-regulated in liver of Balb/cBy mice after 12 week HFD-fed, which can conrtibute to up-regulate free fatty acid beta oxidation and improve insulin signal transduction We used microarrays to detail the global gene expression underlying free fatty acid beta oxidation, unfolded protein response and Akt signal pathway, and then identified up-regulated and down-regulated genes during there process. Overall design: Eight week-old Balb/c and Balb/cBy mice were housed in conventional animal facility with 12 week HFD-fed. total RNA extraction from liver of Balb/c and Balb/cBy mice, and then hybridization on Affymetrix microarray.