Crystal structure of wild type HIV-1 protease in complex with darunavir
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Crystal structure of wild type HIV-1 protease in complex with darunavir Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease Authors: Yedidi, R.S, Garimella, H, Palmer, I, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. Deposit date: 2012-10-16 Release date: 2013-07-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety. Antimicrob.Agents Chemother., 57, 2013
创建时间：
2012-10-16
