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Structure of full-length human AMPK (a2b1g1) in complex with a small molecule activator SC4

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Structure of full-length human AMPK (a2b1g1) in complex with a small molecule activator SC4 Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... Authors: Ngoei, K.R.W, Langendorf, C.G, Ling, N.X.Y, Hoque, A, Johnson, S, Camerino, M.C, Walker, S.R, Bozikis, Y.E, Dite, T.A, Ovens, A.J, Smiles, W.J, Jacobs, R, Huang, H, Parker, M.W, Scott, J.W, Rider, M.H, Kemp, B.E, Foitzik, R.C, Baell, J.B, Oakhill, J.S. Deposit date: 2017-09-19 Release date: 2018-04-25 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4. Cell Chem Biol, 25, 2018
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2017-09-19
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