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Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

ChEBI2010-05-27 更新2026-07-21 收录

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胰岛素信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21710 数据链接链接失效反馈

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Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

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2010-05-27

细胞转录组

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To evaluate the global transcriptomic changes induced by Neuronal Regeneration Related Protein (NREP) downregulation, we employed RNA-sequencing in HepG2 cells lacking NREP. Enriched pathway analyses

NIAID Data Ecosystem100

Original data-SIRT1

分子生物学

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Mammalian sirtuin 1 (SIRT1) regulate lipids metabolism and cell proliferation mediated by mTOR signal pathway

NIAID Data Ecosystem60

Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.. Homo sapiens

哺乳期基因表达

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We have utilized the RNA isolated from breast milk fat globule (MFG) from lactating women from 6h to 42 days following delivery using the HumanHT-12 v4 Expression BeadChip (Illumina, Inc) to determine

NIAID Data Ecosystem50

Gene expression profile in Liver, skeletal muscle, brown and white adipose tissues in mice after different interventions. Mus musculus

基因表达

代谢调控

SIRT1 is a NAD+-dependent protein deacetylase. SIRT1 plays key roles in metabolic regulation and adaptation. In this study, we wanted to compare gene expression profile in SIRT1 overexpressing mice to

NIAID Data Ecosystem60

Supporting data for "SH3 domain binding kinase 1 (SBK1) is a novel enhancer of hepatic insulin signaling."

胰岛素信号通路

糖尿病靶点发现

The liver is the central organ for carbohydrate metabolism to maintain the blood glucose concentration within a normal range. Glucose breakdown or synthesis in the liver is tightly regulated by insuli

DataCite Commons2022-01-12 更新60

Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

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