Peptidylarginine deiminase 4 promotes the renal infiltration of neutrophils and exacerbates the TLR7 agonist-induced lupus mice
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145422
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资源简介：
Peptidylarginine deiminase 4 (PAD4), encoded by PADI4, plays critical roles in the immune system. The pathological roles of PAD4 were investigated in lupus model mice. PAD4-regulated pathways were identified by RNA-sequencing of WT and Padi4 KO neutrophils. Neutrophil mRNA profiles of 8 week-old wild type and Padi4-/-, in response to TLR7 agonost (R848), were generated.
创建时间：
2020-07-22
