Estimating the sensitivity of SiteMotif for proteins sharing similarity at each level.

Level-1 constitutes those protein pairs that share high similarity at all levels i.e similar sequence, similar structure, similar binding sites and recognise the same ligand. Whereas for level-2, similarity is observed at all levels except at the sequence with an average sequence identity less than 30%. Level-3 constitutes testing the performance of our method from the known literature reports.