Synthesis of 4-Azaindolines Using Phase-Transfer Catalysis via an Intramolecular Mannich Reaction
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https://figshare.com/articles/dataset/Synthesis_of_4-Azaindolines_Using_Phase-Transfer_Catalysis_via_an_Intramolecular_Mannich_Reaction/11968494
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资源简介：
A series of bifunctional asymmetric phase-transfer catalysts containing
novel fluorine-containing urea groups derived from cinchona alkaloids
have been synthesized and successfully applied in the asymmetric intramolecular
Mannich reaction. The 4-azaindoline products bearing multiple substrates
were obtained in excellent yield (90−99%), with high enantioselectivity
(up to 95%) and diastereoselectivity (up to >99:1).
创建时间：
2020-03-04
